Doctor’s Best Glucosamine Chondroitin MSM is a dietary supplement that may help with pain management by providing support for joint health, flexibility and comfort. This product combines three ingredients that the maker of this supplement claims to be “proven and purified.”

According to the manufacturer, these combined ingredients help the body to produce proteoglycans in healthy joints. Proteoglycans help in the maintenance of optimal joint structure, enhancing the function of healthy joints.

Doctor’s Best Glucosamine Chondroitin MSM Ingredients

The three main ingredients within the formula include:

  • Glucosamine Sulfate 2KCI
  • Chondroitin Sulfate
  • MSM

Why was this combination of ingredients selected? On the official Doctor’s Best product page for Doctor’s Best Glucosamine Chondroitin MSM it is said that glucosamine is an essential building block for proteoglycans and glycosaminoglycans. Glucosamine sulfate aids in the maintenance of joint health through its ability to function as a component of and promote the formation of glycosaminoglycans and the hyaluronic acid that is vital for forming proteoglycans in healthy joints.

Chondroitin sulfate and keratin sulfate are glycosaminoglycans. These long polysaccharide molecules are a magnet for water because of the negative charges of their specific sulfate groups.  This combo of solid and liquid provides joints with a compressible quality that may help stimulate healthy joint function.

MSM is composed of two oxygen atoms and two methyl groups that are bound to a sulfur atom. MSM is responsible for enabling important metabolic functions, among which are enzyme regulation and energy transduction. It is thought to help encourage the integrity and resilience of joints.

Is Glucosamine Truly Beneficial for Joint Point?

Research has found that in some cases, such as in the treatment of osteoarthritis, it may be beneficial, even when combined with chondroitin. That said, more clinical evidence is needed to determine just how effective it might be for this type of pain management.

Additionally, it should be noted that glucosamine should not be taken by individuals with a shellfish allergy as it is derived from the shells of crustaceans (e.g. lobster, shrimp, crab, etc.). It may also worsen asthma. Moreover, glucosamine is not without side effects. Oral use of glucosamine sulfate can cause:

  • Headache
  • Heartburn
  • Nausea
  • Constipation
  • Diarrhea
  • Drowsiness
  • Skin reactions

Is it Worth Taking?

Doctor’s Best Glucosamine Chondroitin MSM appears to be a reputable product. That being said, whether or not it will help you to manage joint pain is another matter altogether. Although some people do find that taking glucosamine supplements are beneficial, others find that they offer no relief at all. Ultimately, if you are considering taking glucosamine supplements to help you manage pain or for joint support, it would be in your best interest to first consult with your healthcare provider.